What is Ubrogepant?
Ubrogepant is a drug which is recommended to cure migraines with or without aura. However, it does not foreclose a headache due to migraine. This med may also be used for purposes not mentioned in this concise medication directory.
What are the common conditions in which Ubrogepant prescribed?
This drug is advised to cure migraines with or without aura. Although, it does not forestall migraine headaches.
How should I take Ubrogepant?
Strictly adhere to the instructions on the prescription label and use it in the suggested amounts and for advised duration only. The medication can be used along with or without food. But you need to avoid grapefruit and its juice.
After taking this medication:
- If your headache does not alleviate or is not completely over, or it retreats: have a second tablet though only if 2 hours have been passed since your first tablet.
- If the symptoms do not show any signs of improvement, do not take no more pills and visit your doctor.
Avoid using a second tablet within 24 hours in case you have had a grapefruit product, or if you also used any of the below-mentioned medicines:
- Verapamil
- Ciprofloxacin
- Cyclosporine
- Fluconazole
- Fluvoxamine
Inform your doctor if you have experienced 8 or more headaches in a month (30 days). Apprize the clinician if the med does not work, and you continue to have migraine attacks as before.
Store at room temperature in a air-cooled and dry spot.
Ubrogepant dosing details
Typical Adult Dosage for Migraine:
- Starting dose: 50 to 100 mg orally, once
- After 2 hours, a second dosage may be used if required
Maximum dosage: 200 mg in 24-hour period
Points of note:
- The safety of curing 8+ migraines in a month period is undiscovered.
Use: For the acute cure of migraine with or without aura.
When you should not take Ubrogepant?
Particular medications can trigger undesirable or perilous effects when taken with this drug. The treatment plan may be altered in case you use any of the following medicines:
- An antibiotic: clarithromycin, telithromycin
- Antifungal drugs: Itraconazole, ketoconazole
- Antiviral medicine to cure HIV/ AIDS: indinavir, nelfinavir, ritonavir, saquinavir
- Nefazodone
Acquaint your doctor if you have ever encountered:
- Kidney conditions
- Liver ailment
It is yet undiscovered if this medicine will damage the foetus. So, communicate to your doctor in case you are pregnant or plan to get pregnant in the near future.
Although, suffering from migraine headaches through the pregnancy can trigger complications like eclampsia (lethally high blood pressure, which can cause life-threatening risk to the baby as well as the mother) or diabetes. The gains of treating the migraine attacks may prevail over any potent risks to the baby. It may not be safe to suckle the baby while taking this medication. You may consult your doctor about the associated perils.
Ubrogepant is not sanctioned for use by those less than 18 years of age. Inform your doctor regarding all the medications you presently take, and started or stopped using. There are several drugs that can interact with the working of the medicine and should not be taken at the same time.
What are the possible side effects of Ubrogepant?
If you experience symptoms of allergic response to the medication such as hives, shallow breath, inflammation in your face or throat, seek immediate medical attention.
Usual side effects may comprise:
- Nausea
- Sleepiness
This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about other side effects.
What to do if I miss the dose?
As this medicine is taken when required, it does not have any dosing plan. However, avoid taking more than 200 milligrams in a period of 24-hours. And also, do not take it for more than 8 migraine headaches in a month.
Common Drug Interaction with Ubrogepant
Often it is unsafe to take particular medicines with Ubrogepant simultaneously. Since, this can impact the blood concentrations of other medicines you use, which could further the side effects or even reduce the efficacy of the medicines. Inform your doctor about the medicines you currently use, and started or stopped using recently.
There are several drugs that can intervene with the med, particularly:
- Cyclosporine
- Curcumin (turmeric)
- Eltromobopag
- Fluconazole
- Fluvoxamine
- Phenytoin
- St. John’s Wort
- Antibiotic: rifampin, ciprofloxacin
- Barbiturate: phenobarbital, secobarbital, butabarbital
- Heart or blood pressure medication: verapamil, carvedilol, quinidine
There are several drugs that can interfere with the working of this drug. Other medications may interact with this medicine, including prescription and over-the-counter drugs, vitamins, and herbal supplements. This is not the complete list of drug interactions.
Bottom line
Ubrogepant is a drug recommended for treating migraines with or without aura. However, it cannot prevent such headaches. Being a strict prescriptive medicine, it should not be taken without a doctor’s consultation. Strictly follow all the instructions while using this drug, else serious consequences may ensue.
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